Development of triazole-based PKC-inhibitors to overcome resistance to EGFR inhibitors in EGFR-mutant lung cancers.

Lee, Pei-Chih; Kumar, Vathan; Sivakumar, Govindan; Tseng, Tzu-Yu; Li, Yi-Chuan; Jiang, Yu-Cyuan; Hsiao, Yu-Chun; Lin, Hsiang-Wen; Chang, Chih-Shiang; Hung, Mien-Chie

Lee, Pei-Chih; Kumar, Vathan; Sivakumar, Govindan; Tseng, Tzu-Yu; Li, Yi-Chuan; Jiang, Yu-Cyuan; Hsiao, Yu-Chun; Lin, Hsiang-Wen; Chang, Chih-Shiang; Hung, Mien-Chie.

Afiliación

Lee PC; Graduate Institute of Biomedical Sciences, China Medical University Taichung, Taiwan.
Kumar V; Research Center for Cancer Biology, China Medical University Taichung, Taiwan.
Sivakumar G; Cancer Biology and Precision Therapeutics Center, China Medical University Taichung, Taiwan.
Tseng TY; School of Pharmacy, College of Pharmacy, China Medical University Taichung, Taiwan.
Li YC; Drug Development Center, China Medical University Taichung, Taiwan.
Jiang YC; School of Pharmacy, College of Pharmacy, China Medical University Taichung, Taiwan.
Hsiao YC; Drug Development Center, China Medical University Taichung, Taiwan.
Lin HW; Graduate Institute of Biomedical Engineering, National Chung Hsing University Taichung, Taiwan.
Chang CS; Graduate Institute of Biomedical Sciences, China Medical University Taichung, Taiwan.
Hung MC; Research Center for Cancer Biology, China Medical University Taichung, Taiwan.

Am J Cancer Res ; 13(10): 4693-4707, 2023.

Article en En | MEDLINE | ID: mdl-37970360

Palabras clave

EGFR; PKC inhibitor; Protein kinase C; lung cancer; resistance

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Cancer Res Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos

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