Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of ß-amino acid-containing cyclic derivatives and heterologous production of ciromicin A.

Seibel, Elena; Um, Soohyun; Dayras, Marie; Bodawatta, Kasun H; de Kruijff, Martinus; Jønsson, Knud A; Poulsen, Michael; Kim, Ki Hyun; Beemelmanns, Christine

Seibel, Elena; Um, Soohyun; Dayras, Marie; Bodawatta, Kasun H; de Kruijff, Martinus; Jønsson, Knud A; Poulsen, Michael; Kim, Ki Hyun; Beemelmanns, Christine.

Afiliación

Seibel E; Chemical Biology of Microbe-Host Interactions, Leibniz institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (HKI), Beutenbergstraße 11a, 07745, Jena, Germany.
Um S; Anti-Infectives from Microbiota, Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS), Campus E8.1, 66123, Saarbrücken, Germany.
Dayras M; Chemical Biology of Microbe-Host Interactions, Leibniz institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (HKI), Beutenbergstraße 11a, 07745, Jena, Germany.
Bodawatta KH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Songdogwahak-ro, Incheon, 12983, Republic of Korea.
de Kruijff M; Anti-Infectives from Microbiota, Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS), Campus E8.1, 66123, Saarbrücken, Germany.
Jønsson KA; Globe Institute, Section for Molecular Ecology and Evolution, University of Copenhagen, 1350, Copenhagen K, Denmark.
Poulsen M; Natural History Museum of Denmark - Research and Collections, University of Copenhagen, 2100, Copenhagen East, Denmark.
Kim KH; Anti-Infectives from Microbiota, Helmholtz-Institut für Pharmazeutische Forschung Saarland (HIPS), Campus E8.1, 66123, Saarbrücken, Germany.
Beemelmanns C; Natural History Museum of Denmark - Research and Collections, University of Copenhagen, 2100, Copenhagen East, Denmark.

Commun Chem ; 6(1): 257, 2023 Nov 20.

Article en En | MEDLINE | ID: mdl-37985888

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Commun Chem Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

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