APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest.

Mouery, Brandon L; Baker, Eliyambuya M; Mills, Christine A; Herring, Laura E; Fleifel, Dalia; Cook, Jeanette Gowen

Mouery, Brandon L; Baker, Eliyambuya M; Mills, Christine A; Herring, Laura E; Fleifel, Dalia; Cook, Jeanette Gowen.

Afiliación

Mouery BL; Curriculum in Genetics and Molecular Biology. The University of North Carolina at Chapel Hill. Chapel Hill, NC 27599, USA.
Baker EM; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill. Chapel Hill, NC 27599.
Mills CA; Immuno-Oncology, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY USA.
Herring LE; UNC Proteomics Core Facility, Department of Pharmacology. The University of North Carolina at Chapel Hill. Chapel Hill, NC 27599, USA.
Fleifel D; Department of Pharmacology. The University of North Carolina at Chapel Hill. Chapel Hill NC, 27599, USA.
Cook JG; UNC Proteomics Core Facility, Department of Pharmacology. The University of North Carolina at Chapel Hill. Chapel Hill, NC 27599, USA.

bioRxiv ; 2023 Nov 09.

Article en En | MEDLINE | ID: mdl-37986787

Palabras clave

APC/C; CDK4/6; Cell cycle arrest; Palbociclib; breast cancer; genome instability; replication stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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