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S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis.
Deng, Liwen; Costa, Flavia; Blake, Kimbria J; Choi, Samantha; Chandrabalan, Arundhasa; Yousuf, Muhammad Saad; Shiers, Stephanie; Dubreuil, Daniel; Vega-Mendoza, Daniela; Rolland, Corinne; Deraison, Celine; Voisin, Tiphaine; Bagood, Michelle D; Wesemann, Lucia; Frey, Abigail M; Palumbo, Joseph S; Wainger, Brian J; Gallo, Richard L; Leyva-Castillo, Juan-Manuel; Vergnolle, Nathalie; Price, Theodore J; Ramachandran, Rithwik; Horswill, Alexander R; Chiu, Isaac M.
Afiliación
  • Deng L; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA.
  • Costa F; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Blake KJ; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA.
  • Choi S; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA.
  • Chandrabalan A; Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario N6A 5C1, Canada.
  • Yousuf MS; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.
  • Shiers S; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.
  • Dubreuil D; Departments of Neurology and Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Vega-Mendoza D; Division of Immunology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Rolland C; IRSD, Université de Toulouse, INSERM, INRAe, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France.
  • Deraison C; IRSD, Université de Toulouse, INSERM, INRAe, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France.
  • Voisin T; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA.
  • Bagood MD; Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.
  • Wesemann L; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA.
  • Frey AM; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA.
  • Palumbo JS; Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Wainger BJ; Departments of Neurology and Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Gallo RL; Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.
  • Leyva-Castillo JM; Division of Immunology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Vergnolle N; IRSD, Université de Toulouse, INSERM, INRAe, ENVT, Université Toulouse III-Paul Sabatier (UPS), Toulouse, France.
  • Price TJ; Department of Neuroscience and Center for Advanced Pain Studies, University of Texas at Dallas, Richardson, TX 75080, USA.
  • Ramachandran R; Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario N6A 5C1, Canada.
  • Horswill AR; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Chiu IM; Department of Immunology, Harvard Medical School, Boston, MA 02215, USA. Electronic address: isaac_chiu@hms.harvard.edu.
Cell ; 186(24): 5375-5393.e25, 2023 11 22.
Article en En | MEDLINE | ID: mdl-37995657
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptido Hidrolasas / Prurito / Infecciones Estafilocócicas / Staphylococcus aureus / Receptor PAR-1 Límite: Animals / Humans Idioma: En Revista: Cell Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptido Hidrolasas / Prurito / Infecciones Estafilocócicas / Staphylococcus aureus / Receptor PAR-1 Límite: Animals / Humans Idioma: En Revista: Cell Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos