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Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy.
Chehelgerdi, Matin; Behdarvand Dehkordi, Fereshteh; Chehelgerdi, Mohammad; Kabiri, Hamidreza; Salehian-Dehkordi, Hosein; Abdolvand, Mohammad; Salmanizadeh, Sharareh; Rashidi, Mohsen; Niazmand, Anoosha; Ahmadi, Saba; Feizbakhshan, Sara; Kabiri, Saber; Vatandoost, Nasimeh; Ranjbarnejad, Tayebeh.
Afiliación
  • Chehelgerdi M; Novin Genome (NG) Lab, Research and Development Center for Biotechnology, Shahrekord, Iran.
  • Behdarvand Dehkordi F; Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
  • Chehelgerdi M; Novin Genome (NG) Lab, Research and Development Center for Biotechnology, Shahrekord, Iran.
  • Kabiri H; Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
  • Salehian-Dehkordi H; Novin Genome (NG) Lab, Research and Development Center for Biotechnology, Shahrekord, Iran. Chehelgerdi1992@gmail.com.
  • Abdolvand M; Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran. Chehelgerdi1992@gmail.com.
  • Salmanizadeh S; Novin Genome (NG) Lab, Research and Development Center for Biotechnology, Shahrekord, Iran.
  • Rashidi M; Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
  • Niazmand A; College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
  • Ahmadi S; Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
  • Feizbakhshan S; Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Hezar-Jereeb Street, Isfahan, 81746-73441, Iran.
  • Kabiri S; Department Pharmacology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  • Vatandoost N; The Health of Plant and Livestock Products Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
  • Ranjbarnejad T; Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
Mol Cancer ; 22(1): 189, 2023 11 28.
Article en En | MEDLINE | ID: mdl-38017433
The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental factors. iPSCs offer a distinctive platform for investigating the origin of cancer, paving the way for novel approaches to cancer treatment, drug testing, and tailored medical interventions. This review article will provide an overview of the science behind iPSCs, the current limitations and challenges in iPSC-based cancer therapy, the ethical and social implications, and the comparative analysis with other stem cell types for cancer treatment. The article will also discuss the applications of iPSCs in tumorigenesis, the future of iPSCs in tumorigenesis research, and highlight successful case studies utilizing iPSCs in tumorigenesis research. The conclusion will summarize the advancements made in iPSC-based tumorigenesis research and the importance of continued investment in iPSC research to unlock the full potential of these cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Neoplasias Límite: Humans Idioma: En Revista: Mol Cancer Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Neoplasias Límite: Humans Idioma: En Revista: Mol Cancer Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido