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Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias.
Nishida, Yuki; Ishizawa, Jo; Ayoub, Edward; Montoya, Rafael Heinz; Ostermann, Lauren B; Muftuoglu, Muharrem; Ruvolo, Vivian R; Patsilevas, Tallie; Scruggs, Darah A; Khazaei, Shayaun; Mak, Po Yee; Tao, Wenjing; Carter, Bing Z; Boettcher, Steffen; Ebert, Benjamin L; Daver, Naval G; Konopleva, Marina; Seki, Takahiko; Kojima, Kensuke; Andreeff, Michael.
Afiliación
  • Nishida Y; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ishizawa J; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ayoub E; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Montoya RH; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ostermann LB; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Muftuoglu M; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ruvolo VR; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Patsilevas T; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Scruggs DA; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Khazaei S; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Mak PY; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Tao W; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Carter BZ; Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Boettcher S; Department of Medical Oncology and Haematology, University Hospital Zurich, University of Zurich, Zurich 8091, Switzerland.
  • Ebert BL; Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, The Broad Institute, Boston, MA 02115, USA.
  • Daver NG; Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, The Broad Institute, Boston, MA 02115, USA.
  • Konopleva M; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Seki T; Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Kojima K; Section of Leukemia Biology Research, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Andreeff M; Daiichi Sankyo Co. Ltd., Tokyo 103-8426, Japan.
Sci Adv ; 9(48): eadh1436, 2023 12.
Article en En | MEDLINE | ID: mdl-38019903
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteína p53 Supresora de Tumor Límite: Humans Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteína p53 Supresora de Tumor Límite: Humans Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos