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New discoveries on how DICER efficiently processes pre-miRNA.
Weng, Qi; Wu, Qi; Zheng, Quan.
Afiliación
  • Weng Q; Department of Pharmacy Quzhou People's Hospital The Quzhou Affiliated Hospital of Wenzhou Medical University Quzhou China.
  • Wu Q; Core Facility Quzhou People's Hospital The Quzhou Affiliated Hospital of Wenzhou Medical University Quzhou China.
  • Zheng Q; Core Facility Quzhou People's Hospital The Quzhou Affiliated Hospital of Wenzhou Medical University Quzhou China.
MedComm (2020) ; 4(6): e430, 2023 Dec.
Article en En | MEDLINE | ID: mdl-38034100
The latest study identified the "GYM motif" on precursor microRNA (pre-miRNA) for the first time and highlighted its key role in DICER specifically recognizing and efficiently cleaving pre-miRNA to produce miRNA. In addition, the dicing state of DICER efficiently processing pre-miRNA was revealed, which was previously difficult to capture.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: MedComm (2020) Año: 2023 Tipo del documento: Article Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: MedComm (2020) Año: 2023 Tipo del documento: Article Pais de publicación: China