Inhibition of ferroptosis by POLE2 in gastric cancer cells involves the activation of NRF2/GPX4 pathway.

Jian, Hui; Chen, Zhi-Qiang; Du, Heng; Liao, Ting; Sun, Yi-Chen; Ke, Dong; Yu, Yang

Jian, Hui; Chen, Zhi-Qiang; Du, Heng; Liao, Ting; Sun, Yi-Chen; Ke, Dong; Yu, Yang.

Afiliación

Jian H; Department of Gastrointestinal Surgery, Affiliated Hospital of Jianghan University, Wuhan, Hubei, China.
Chen ZQ; Department of Gastrointestinal Surgery, Affiliated Hospital of Jianghan University, Wuhan, Hubei, China.
Du H; Department of Gastrointestinal Surgery, Huanggang Central Hospital Affiliated to Yangtze University, Huanggang, Hubei, China.
Liao T; Department of Gastroenterology, Affiliated Hospital of Jianghan University, Wuhan, Hubei, China.
Sun YC; Department of Oncology, Affiliated Hospital of Jianghan University, Wuhan, Hubei, China.
Ke D; Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yu Y; Department of Gastrointestinal Surgery, Affiliated Hospital of Jianghan University, Wuhan, Hubei, China.

J Cell Mol Med ; 28(1): e17983, 2024 01.

Article en En | MEDLINE | ID: mdl-38070189

Asunto(s)

Ferroptosis; Neoplasias Gástricas; Humanos; Lentivirus; Factor 2 Relacionado con NF-E2; Nucleotidiltransferasas; Subunidades de Proteína

Palabras clave

GPX4; POLE2; ferroptosis; gastric cancer

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Ferroptosis Límite: Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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