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Using a digital tool to detect early changes in everyday functioning in older adults: A pilot study of the Assessment of Smartphone Everyday Tasks (ASSET).
Dubbelman, Mark A; Hall, Tia C; Levesque, Isabella M; Mimmack, Kayden J; Sikkes, Sietske A M; Fischer, Shira H; Rentz, Dorene M; Sperling, Reisa A; Papp, Kathryn V; Amariglio, Rebecca E; Marshall, Gad A.
Afiliación
  • Dubbelman MA; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.
  • Hall TC; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
  • Levesque IM; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
  • Mimmack KJ; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
  • Sikkes SAM; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.
  • Fischer SH; Department of Neurology Alzheimer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands.
  • Rentz DM; Faculty of Behavioral and Movement Sciences Clinical Developmental Psychology and Clinical Neuropsychology Vrije Universiteit Amsterdam Amsterdam The Netherlands.
  • Sperling RA; RAND Corporation Boston Massachusetts USA.
  • Papp KV; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.
  • Amariglio RE; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
  • Marshall GA; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.
Alzheimers Dement (Amst) ; 15(4): e12506, 2023.
Article en En | MEDLINE | ID: mdl-38111596
ABSTRACT

INTRODUCTION:

To investigate the utility of a new digital tool for measuring everyday functioning in preclinical Alzheimer's disease, we piloted the Assessment of Smartphone Everyday Tasks (ASSET) application.

METHODS:

Forty-six participants (50.3 ± 27.1 years; 67% female; 20 young unimpaired, 17 old unimpaired, 9 mildly cognitively impaired) completed ASSET 7 times. ASSET comprises two main tasks, simulating a Patient Portal and a Calendar. We assessed ASSET's internal consistency, test-retest reliability, and user experience.

RESULTS:

ASSET main tasks correlated with each other (r = 0.75, 95% confidence interval [CI] = [0.58, 0.86]). Performance on ASSET's Patient Portal related to cognition (r = 0.64, 95% CI = [0.42, 0.79]) and observer ratings of everyday functioning (r = 0.57, 95% CI = [0.24, 0.79]). Test-retest reliability was good (intraclass correlation coefficient = 0.87, 95% CI = [0.77, 0.93]). Most participants rated their experience with ASSET neutrally or positively.

DISCUSSION:

ASSET is a promising smartphone-based digital assessment of everyday functioning. Future studies may investigate its utility for early diagnosis and evaluation of treatment of Alzheimer's disease.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Alzheimers Dement (Amst) Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Alzheimers Dement (Amst) Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos