[Effectiveness and safety of endosonography-guided liver biopsy in liver disease at a level III public hospital]. / Efectividad y seguridad de la biopsia hepática guiada por endosonografía en enfermedad hepática en un hospital público de nivel III.
Rev Gastroenterol Peru
; 43(4): 341-347, 2023.
Article
en Es
| MEDLINE
| ID: mdl-38228300
ABSTRACT
Parenchymal liver diseases are commonly evaluated by laboratory and imaging studies. However, in some cases a liver biopsy is required. Endoscopic ultrasonography-guided liver biopsy (EUS-LB) has been reported as a procedure with high diagnostic yield (90-100%) with low adverse event profile, but there are not studies which report about the experience and technique in our country. OBJECTIVE:
Determinate the effectiveness and the safety of endosonography-guided liver biopsy in liver parenchymal disease. MATERIALS ANDMETHODS:
A prospective study was conducted at a III-2 level of care Public Hospital in Lima, Peru. It included patients over 18 years of age with suspicion of parenchymal liver disease who underwent EUS-LB for study hepatic parenchymal disease since March of 2018 to October of 2022.RESULTS:
The diagnostic yield of the biopsies was 77.02%, with a mean length of the sample of 13.98mm (standard deviation 7.34) and a median of 8 complete portal spaces (0-50). Only 31.25% of the procedures were performed with a fine needle biopsy (FNB), finding a significant difference between the type of needle and the diagnostic yield (p=0.01). The most common histopathological diagnosis was autoinmune hepatitis. There were 2.08% of post-procedure complications.CONCLUSIONS:
EUS-LB for the diagnosis of liver parenchymal disease had a diagnostic yield close to 80% in our region with a low profile of adverse events. However, more prospectives studies with a larger number of patients are required.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Endosonografía
/
Hepatopatías
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Adolescent
/
Adult
/
Humans
Idioma:
Es
Revista:
Rev Gastroenterol Peru
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2023
Tipo del documento:
Article