Your browser doesn't support javascript.
loading
Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey.
Eruygur, Nuraniye; Tuzcu, Nevin; Tugay, Osman; Yilmaz, Mustafa Abdullah; Cakir, Oguz.
Afiliación
  • Eruygur N; Department of Pharmacognosy, Faculty of Pharmacy, Selcuk University, Konya, Turkey.
  • Tuzcu N; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Selcuk University, Konya, Turkey.
  • Tugay O; Department of Pharmaceutical Botany, Faculty of Pharmacy, Selcuk University, Konya, Turkey.
  • Yilmaz MA; Department of Analytical Chemistry, Faculty of Pharmacy, Dicle University, Diyarbakir Sur, Turkey.
  • Cakir O; Science and Technology Research and Application Center, Dicle University, Diyarbakir, Turkey.
Int J Environ Health Res ; 34(9): 3334-3347, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38245842
ABSTRACT
The methanol extract of Inula viscosa (IVM) was investigated for its antioxidant potential using the DPPH and ABTS radical scavenging as well as iron chelating assays (ICA). The total phenol (TPC) and flavonoid contents (TFC) of IVM were determined using the Folin-Ciocalteu and aluminum trichloride methods, respectively. Antimicrobial activity of different concentrations of I. viscosa methanol extract was investigated by disc diffusion and broth microdilution method. The IVM extract was found to be containing TPC (236.78 ± 7.63 mg GAE/g) and TFC (94.36 ± 1.86 mg QE/g). Antioxidant activity IC50 values for the DPPH, ABTS and ICA assays were found to be 277.7 ± 3.68, 2.44 ± 0.02, and 222.1 ± 0.71 µg/mL, respectively. The MIC values of the IVM on the tested microorganisms ranged from 0.48 to 7.81 mg/mL. Furthermore, IVM extract was demonstrated 18.32 ± 1.37%, 23.06 ± 1.05%, 4.72 ± 0.13%, 15.13 ± 0.37% and 37.64 ± 4.02% inhibition against tyrosinase, α-amylase, α-glucosidase, AChE and BChE, respectively. In the results of LC-MS/MS analysis, acacetin, quercetin, chlorogenic acid and protocatechuic acid were determined as most dominant compounds. These findings suggested that this plant may be a natural resource for creating novel medicinal compounds.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Inula / Fitoquímicos / Antioxidantes País/Región como asunto: Asia Idioma: En Revista: Int J Environ Health Res Asunto de la revista: SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Inula / Fitoquímicos / Antioxidantes País/Región como asunto: Asia Idioma: En Revista: Int J Environ Health Res Asunto de la revista: SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Reino Unido