Repeatability and reproducibility of quantitative OCT angiography measurements from table-top and portable Flex Spectralis devices.
Graefes Arch Clin Exp Ophthalmol
; 262(6): 1785-1793, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38270629
ABSTRACT
PURPOSE:
The recent development of a portable investigational handheld OCT-angiography (OCTA) device has allowed for expansion of imaging into the operating room (OR) in addition to standard in-clinic imaging. The aim of this study was to assess intravisit repeatability and intervisit reproducibility of retinal microvasculature measures and central retinal thickness for in-clinic table-top and portable OR compatible OCTA devices.METHODS:
Repeated 10 × 10 OCTA images were acquired in 20 healthy adult participants on two separate visit days using Spectralis spectral-domain OCTA table-top and investigational armature suspended Flex systems. Intravisit and intervisit intraclass correlation coefficients and average absolute percent difference were calculated for quantitative microvasculature measures and CRT.RESULTS:
120 OCTA images were acquired from 20 subjects (n = 20, mean age 26.7 ± 1.61 years, range 24-30 years) with both devices across two separate imaging days. FAZ and CRT measurements had near complete intravisit and intervisit agreement with ICCs between .97 and 1 for both table-top (FAZ ICC .97, .97; CRT ICC .98-1, .98-.99) and Flex (FAZ ICC .97, .95; CRT ICC .99-1, .98-.99) devices. Vessel density measures demonstrated greater variance with only fair to strong agreement (ICC .32-.75) and average absolute percent differences ranging from 2.96 to 6.63%.CONCLUSION:
FAZ and CRT measures for both devices demonstrated high repeatability and reproducibility; retinal vessel density measures demonstrated less. Differences of less than 7% for retinal microvasculature measurements across time and devices are most likely attributable to expectable variance between repeat scans.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vasos Retinianos
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Angiografía con Fluoresceína
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Tomografía de Coherencia Óptica
Límite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Graefes Arch Clin Exp Ophthalmol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos