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The contributions of clinical disease activity, functional disability, and illness intrusiveness to depressive symptoms in pediatric inflammatory bowel disease.
Edwards, Clayton S; Baudino, Marissa N; Roberts, Caroline M; Basile, Nathan L; Dattilo, Taylor M; Gamwell, Kaitlyn L; Jacobs, Noel J; Edwards, Desti S; Tung, Jeanne; Parker, Colton V; Chaney, John M.
Afiliación
  • Edwards CS; Center for Pediatric Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
  • Baudino MN; Baylor College of Medicine - Texas Children's Hospital, Houston, Texas, USA.
  • Roberts CM; Baylor College of Medicine - Texas Children's Hospital, Houston, Texas, USA.
  • Basile NL; Center for Pediatric Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
  • Dattilo TM; Center for Pediatric Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
  • Gamwell KL; School of Medicine, University of South Carolina, Columbia, South Carolina, USA.
  • Jacobs NJ; Department of Psychology, Oklahoma City University, Oklahoma City, Oklahoma, USA.
  • Edwards DS; Pediatric Gastroenterology, Oklahoma Children's Hospital OU Health, Oklahoma City, Oklahoma, USA.
  • Tung J; Pediatric Gastroenterology, Oklahoma Children's Hospital OU Health, Oklahoma City, Oklahoma, USA.
  • Parker CV; Center for Pediatric Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
  • Chaney JM; Center for Pediatric Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
J Pediatr Gastroenterol Nutr ; 78(1): 77-84, 2024 01.
Article en En | MEDLINE | ID: mdl-38291697
ABSTRACT

BACKGROUND:

Clinical disease activity associated with inflammatory bowel disease (IBD) can place physical limitations on youths' activities of daily living. In turn, functional limitations potentially contribute to youths' heightened experience of IBD-induced intrusions on a wide range of routine and valued activities (i.e., illness intrusiveness), which can increase their risk for depressive symptoms. The present study examined the contributions of clinical disease activity, functional disability, and illness intrusiveness to depressive symptoms in youth with IBD.

METHODS:

Youth (N = 180) completed the Functional Disability Inventory (FDI), Illness Intrusiveness Scale-Child (IIS-C), and Children's Depression Inventory-2 (CDI-2). Physicians completed the Physicians Global Assessment of disease activity (PGA).

RESULTS:

Results revealed a mediating effect for functional disability in the association between disease activity and depressive symptoms (PGA → FDI → CDI-2); illness intrusiveness mediated the association between functional disability and depressive symptoms (i.e., FDI → IIS-C → CDI-2). Serial mediation revealed that clinical disease activity conferred an indirect effect on youth depressive symptoms through the sequential effects of functional disability and illness intrusiveness (i.e., PGA → FDI → IIS-C → CDI-2).

CONCLUSIONS:

Taken together, these findings indicate that youth who encounter more physical limitations as a function of clinical disease activity are more likely to experience an amplified sense of IBD-related intrusions on their ability to participate in meaningful activities. In turn, heightened illness intrusiveness increases the likelihood of depressive symptoms. Clinical interventions that help youth maintain adequate functional ability in the face of IBD disease activity and encourage involvement in positively valued activities could decrease the negative impact of IBD on youths' emotional adjustment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Depresión Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Adolescent / Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Depresión Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Adolescent / Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos