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HiOmics: A cloud-based one-stop platform for the comprehensive analysis of large-scale omics data.
Li, Wen; Zhang, Zhining; Xie, Bo; He, Yunlin; He, Kangming; Qiu, Hong; Lu, Zhiwei; Jiang, Chunlan; Pan, Xuanyu; He, Yuxiao; Hu, Wenyu; Liu, Wenjian; Que, Tengcheng; Hu, Yanling.
Afiliación
  • Li W; Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
  • Zhang Z; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Guangxi Medical University, Nanning, Guangxi, China.
  • Xie B; Key Laboratory of Biological Molecular Medicine Research (Guangxi Medical University), Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
  • He Y; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
  • He K; Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
  • Qiu H; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
  • Lu Z; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
  • Jiang C; Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
  • Pan X; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
  • He Y; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
  • Hu W; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
  • Liu W; School of Basic Medicine, Guangxi Medical University, Nanning, Guangxi, China.
  • Que T; Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China.
  • Hu Y; Guangxi Henbio Biotechnology Co., Ltd., Nanning, Guangxi, China.
Comput Struct Biotechnol J ; 23: 659-668, 2024 Dec.
Article en En | MEDLINE | ID: mdl-38292471
ABSTRACT
Analyzing the vast amount of omics data generated comprehensively by high-throughput sequencing technology is of utmost importance for scientists. In this context, we propose HiOmics, a cloud-based platform equipped with nearly 300 plugins designed for the comprehensive analysis and visualization of omics data. HiOmics utilizes the Element Plus framework to craft a user-friendly interface and harnesses Docker container technology to ensure the reliability and reproducibility of data analysis results. Furthermore, HiOmics employs the Workflow Description Language and Cromwell engine to construct workflows, ensuring the portability of data analysis and simplifying the examination of intricate data. Additionally, HiOmics has developed DataCheck, a tool based on Golang, which verifies and converts data formats. Finally, by leveraging the object storage technology and batch computing capabilities of public cloud platforms, HiOmics enables the storage and processing of large-scale data while maintaining resource independence among users.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Comput Struct Biotechnol J Año: 2024 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Comput Struct Biotechnol J Año: 2024 Tipo del documento: Article País de afiliación: China
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