Two new terpenoids from the branches and leaves of Rhododendron dauricum L. with neuroprotective activity.
Nat Prod Res
; : 1-6, 2024 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-38300706
ABSTRACT
Two new terpenoids were isolated from the branches and leaves of Rhododendron dauricum L., named as rhodayritions A (1) and B (2), together with five known compounds which were identified litseachromolaevane A (3), 11-αH-dihydrodehydrocostus lactone (4), (+)-9ß-hydroxyeudesma-4,11(13)-dien-12-al (5), macrostachyoside B (6) and aglaiabbreviatin E (7), respectively. The structures of isolated compounds were determined by UV, HR-ESI-MS, NMR analysis and X-Ray. Their neuroprotective activity was studied on serum deprivation-induced PC12 cells by the MTT method, compounds 1, 6, and 7 exhibited significant neuroprotective activity at 20 µΜ.
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01-internacional
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MEDLINE
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En
Revista:
Nat Prod Res
Año:
2024
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Article