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Introduction of continuous glucose monitoring (CGM) is a key factor in decreasing HbA1c in war refugee children with type 1 diabetes.
Neuman, V; Vavra, D; Drnkova, L; Pruhova, S; Plachy, L; Kolouskova, S; Obermannova, B; Amaratunga, S A; Konecna, P; Vyzralkova, J; Venhacova, P; Pomahacova, R; Paterova, P; Stichova, L; Skvor, J; Kocourkova, K; Romanova, M; Vosahlo, J; Strnadel, J; Polockova, K; Neumann, D; Slavenko, M; Sumnik, Z.
Afiliación
  • Neuman V; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic. Electronic address: vit.neuman@fnmotol.cz.
  • Vavra D; 3(rd) Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Drnkova L; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Pruhova S; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Plachy L; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Kolouskova S; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Obermannova B; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Amaratunga SA; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Konecna P; Department of Pediatrics, University Hospital Brno, Brno, Czech Republic.
  • Vyzralkova J; Department of Pediatrics, University Hospital Brno, Brno, Czech Republic.
  • Venhacova P; Department of Pediatrics, University Hospital Olomouc, Olomouc, Czech Republic.
  • Pomahacova R; Department of Pediatrics, University Hospital Pilsen, Pilsen, Czech Republic.
  • Paterova P; Department of Pediatrics, University Hospital Pilsen, Pilsen, Czech Republic.
  • Stichova L; Department of Pediatrics, Masaryk Hospital, Usti nad Labem, Czech Republic.
  • Skvor J; Department of Pediatrics, Masaryk Hospital, Usti nad Labem, Czech Republic.
  • Kocourkova K; Department of Pediatrics, Ceske Budejovice Hospital, Ceske Budejovice, Czech Republic.
  • Romanova M; Department of Pediatrics, 3(rd) Faculty of Medicine, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
  • Vosahlo J; Department of Pediatrics, 3(rd) Faculty of Medicine, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
  • Strnadel J; Department of Pediatrics, University Hospital Ostrava, Ostrava, Czech Republic.
  • Polockova K; Department of Pediatrics, University Hospital Ostrava, Ostrava, Czech Republic.
  • Neumann D; Department of Pediatrics, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
  • Slavenko M; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Sumnik Z; Department of Pediatrics, 2(nd) Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Diabetes Res Clin Pract ; 208: 111118, 2024 Feb.
Article en En | MEDLINE | ID: mdl-38309536
ABSTRACT

AIMS:

Our aim was to describe the changes in therapy and diabetes control in Ukrainian war refugee children with diabetes (CwD) during the first year of their stay in Czechia.

METHODS:

A total of 124 CwD (62 male, 62 female) were enrolled into this observational study. Anthropometric, laboratory and diabetes management data were acquired at baseline and at 3 months intervals for 12 months. All CwD were offered a CGM device during their first visit. Generalized Estimating Equation models were fitted in order to estimate the dynamics of studied characteristics.

RESULTS:

Median baseline HbA1c was 58 mmol/mol (IQR [48; 73]mmol/mol) (7.5 %, IQR[6.5;8.8]%). The HbA1c decreased significantly throughout the course of the study at a pace of - 2.2 mmol/mol (-0.2 %pt.) per visit (P = 0.01, CI[-3.2;-1.1]). The pace of the decrease in the average HbA1c was significantly higher in the group of CwD who received CGM in Czechia than in those who already had it from Ukraine by 2.9 mmol/mol (0.27 %pt.) per visit (P < 0.001, CI [-4.4; -1.3]).

CONCLUSIONS:

The steepest decrease in HbA1c was observed in CwD with newly initiated CGM underlining its vital role in improving the glucose control of CwD regardless of their background.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Refugiados / Diabetes Mellitus Tipo 1 Tipo de estudio: Observational_studies / Prognostic_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Refugiados / Diabetes Mellitus Tipo 1 Tipo de estudio: Observational_studies / Prognostic_studies Límite: Child / Female / Humans / Male Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda