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Chiral nanomaterials in tissue engineering.
Yang, Zhenxu; Jaiswal, Arun; Yin, Qiankun; Lin, Xiaoqi; Liu, Lu; Li, Jiarong; Liu, Xiaochen; Xu, Zhejun; Li, Jiao Jiao; Yong, Ken-Tye.
Afiliación
  • Yang Z; School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia. jiaojiao.li@uts.edu.au.
  • Jaiswal A; The University of Sydney Nano Institute, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Yin Q; The Biophotonics and Mechanobioengineering Laboratory, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Lin X; School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia. jiaojiao.li@uts.edu.au.
  • Liu L; The University of Sydney Nano Institute, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Li J; The Biophotonics and Mechanobioengineering Laboratory, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Liu X; School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia. jiaojiao.li@uts.edu.au.
  • Xu Z; The Biophotonics and Mechanobioengineering Laboratory, Faculty of Engineering, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Li JJ; School of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Sydney, New South Wales 2007, Australia.
  • Yong KT; School of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Sydney, New South Wales 2007, Australia.
Nanoscale ; 16(10): 5014-5041, 2024 Mar 07.
Article en En | MEDLINE | ID: mdl-38323627
ABSTRACT
Addressing significant medical challenges arising from tissue damage and organ failure, the field of tissue engineering has evolved to provide revolutionary approaches for regenerating functional tissues and organs. This involves employing various techniques, including the development and application of novel nanomaterials. Among them, chiral nanomaterials comprising non-superimposable nanostructures with their mirror images have recently emerged as innovative biomaterial candidates to guide tissue regeneration due to their unique characteristics. Chiral nanomaterials including chiral fibre supramolecular hydrogels, polymer-based chiral materials, self-assembling peptides, chiral-patterned surfaces, and the recently developed intrinsically chiroptical nanoparticles have demonstrated remarkable ability to regulate biological processes through routes such as enantioselective catalysis and enhanced antibacterial activity. Despite several recent reviews on chiral nanomaterials, limited attention has been given to the specific potential of these materials in facilitating tissue regeneration processes. Thus, this timely review aims to fill this gap by exploring the fundamental characteristics of chiral nanomaterials, including their chiroptical activities and analytical techniques. Also, the recent advancements in incorporating these materials in tissue engineering applications are highlighted. The review concludes by critically discussing the outlook of utilizing chiral nanomaterials in guiding future strategies for tissue engineering design.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanoestructuras / Nanopartículas Idioma: En Revista: Nanoscale Año: 2024 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanoestructuras / Nanopartículas Idioma: En Revista: Nanoscale Año: 2024 Tipo del documento: Article País de afiliación: Australia