Laboratory Assessment of Molluscicidal Activities of Cannabis sativa, Acacia nilotica, and Tinospora cordifolia Against Snail Host of Fasciola spp.
Vector Borne Zoonotic Dis
; 24(6): 382-389, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38364187
ABSTRACT
Background:
The potential molluscicidal extracts, obtained from indigenous plants Cannabis sativa, Acacia nilotica, and Tinospora cordifolia, were tested for toxicity against freshwater pulmonate snail Lymnaea acuminata, an intermediate host of Fasciola hepatica. The organic extracts had a significant effect on young snails. Materials andMethods:
All organic extracts and column-purified fractions gave median lethal concentrations (19-100.05 mg/L; 24 h) that fell well within the threshold level of 100 mg/L, set for a potential molluscicide by the World Health Organization.Results:
The toxicity of T. cordifolia stem acetone extract (96 h LC50 16.08 mg/L) was more pronounced compared with C. sativa leaf ethanol extract (96 h LC50 16.32 mg/L) and A. nilotica leaf ethanol extract (96 h LC50 24.78 mg/L). ß-caryophyllene, gallic acid, and berberine were characterized and identified as active molluscicidal components. Co-migration of ß-caryophyllene (retardation factor [Rf] 0.95), gallic acid (Rf 0.30), and berberine (Rf 0.23) with column-purified parts of Cannabis sativa, Acacia nilotica, and Tinospora cordifolia on thin-layer chromatography demonstrates same Rf value, that is, 0.95, 0.30, and 0.23, respectively.Conclusion:
This study indicates that these extracts thus represent potential plant-derived molluscicides that are worthy of further investigations.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cannabis
/
Extractos Vegetales
/
Tinospora
/
Acacia
/
Moluscocidas
Límite:
Animals
Idioma:
En
Revista:
Vector Borne Zoonotic Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
EPIDEMIOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
India