Mid-life employment trajectories and subsequent memory function and rate of decline in rural South Africa, 2000-22.
Int J Epidemiol
; 53(2)2024 Feb 14.
Article
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| MEDLINE
| ID: mdl-38365967
ABSTRACT
AIM:
To investigate mid-life employment trajectories in relation to later-life memory function and rate of decline in rural South Africa.METHODS:
Data from the Agincourt Health and Socio-Demographic Surveillance System were linked to the 'Health and Ageing in Africa A Longitudinal Study of an INDEPTH Community in South Africa' (HAALSI) in rural Agincourt, South Africa (N = 3133). Employment was assessed every 4 years over 2000-12 as being employed (0, 1, 2 and ≥3 time points), being employed in a higher-skill occupation (0, 1, 2 and ≥3 time points) and dynamic employment trajectories identified using sequence analysis. Latent memory z-scores were assessed over 2014-22. Mixed-effects linear regression models were fitted to examine the associations of interest.RESULTS:
Sustained mid-life employment from 2000-12 (ß = 0.052, 95% CI -0.028 to 0.132, 1 vs 0 time points; ß = 0.163, 95% CI 0.077 to 0.250, 2 vs 0 time points; ß = 0.212, 95% CI 0.128 to 0.296, ≥3 vs 0 time points) and greater time spent in a higher-skill occupation (ß = 0.077, 95% CI -0.020 to 0.175, 1 vs 0 time points; ß = 0.241, 95% CI 0.070 to 0.412, 2 vs 0 time points; ß = 0.361, 95% CI 0.201 to 0.520, ≥3 vs 0 time points) were associated with higher memory scores in 2014/15, but not subsequent rate of memory decline. Moving from a lower-skill to higher-skill occupation was associated with higher memory function, but a faster rate of decline over 2014-22.CONCLUSIONS:
Sustained mid-life employment, particularly in higher-skill occupations, may contribute to later-life memory function in this post-Apartheid South African setting.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Cognición
Límite:
Humans
País/Región como asunto:
Africa
Idioma:
En
Revista:
Int J Epidemiol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos