Complete nucleotide sequence of hepatic 5-aminolaevulinate synthase precursor.
Eur J Biochem
; 150(3): 481-4, 1985 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-3839458
ABSTRACT
Chick embryo liver mitochondrial matrix protein, 5-aminolaevulinate synthase, is synthesised initially as a larger cytosolic precursor. In this report we present the complete nucleotide sequence of a cDNA clone coding for the precursor together with corresponding confirmatory amino acid sequence of peptides derived from purified mature mitochondrial enzyme. The deduced amino acid sequence shows that the precursor consists of mature enzyme of 579 amino acids and an N-terminal extension of 56 amino acids. The latter presequence is highly basic in character as found with other mitochondrial preproteins.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Mitocondrias Hepáticas
/
Precursores Enzimáticos
/
5-Aminolevulinato Sintetasa
Límite:
Animals
Idioma:
En
Revista:
Eur J Biochem
Año:
1985
Tipo del documento:
Article