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Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia.
Carey-Smith, Shannon L; Simad, Maryam H; Panchal, Kunjal; Aya-Bonilla, Carlos; Smolders, Hannah; Lin, Sang; Armitage, Jesse D; Nguyen, Vivien T; Bentley, Kathryn; Ford, Jette; Singh, Sajla; Oommen, Joyce; Laurent, Anouchka P; Mercher, Thomas; Crispino, John D; Montgomery, Andrew P; Kassiou, Michael; Besson, Thierry; Deau, Emmanuel; Meijer, Laurent; Cheung, Laurence C; Kotecha, Rishi S; Malinge, Sébastien.
Afiliación
  • Carey-Smith SL; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA.
  • Simad MH; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Panchal K; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA.
  • Aya-Bonilla C; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Smolders H; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Lin S; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Armitage JD; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Nguyen VT; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Bentley K; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Ford J; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Singh S; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Oommen J; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA.
  • Laurent AP; U1170 INSERM, Gustave Roussy, Villejuif.
  • Mercher T; U1170 INSERM, Gustave Roussy, Villejuif.
  • Crispino JD; Department of Hematology, St Jude Children's Hospital, Memphis, TN.
  • Montgomery AP; School of Chemistry, University of Sydney, NSW.
  • Kassiou M; School of Chemistry, University of Sydney, NSW.
  • Besson T; University Rouen Normandie, INSA Rouen Normandie, CNRS, COBRA UMR 6014, 76000.
  • Deau E; Perha Pharmaceuticals, Perharidy Peninsula, Roscoff.
  • Meijer L; Perha Pharmaceuticals, Perharidy Peninsula, Roscoff.
  • Cheung LC; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA, Australia; Curtin Health Innovation Research Institute, Curtin University, Perth, WA.
  • Kotecha RS; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA, Australia; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia; University of Western Australia
  • Malinge S; Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia; Curtin Medical School, Curtin University, Perth, WA, Australia; University of Western Australia, Perth, WA. sebastien.malinge@telethonkids.org.au.
Haematologica ; 109(7): 2309-2315, 2024 07 01.
Article en En | MEDLINE | ID: mdl-38426275

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Proteínas Serina-Treonina Quinasas / Síndrome de Down / Inhibidores de Proteínas Quinasas / Leucemia-Linfoma Linfoblástico de Células Precursoras / Quinasas DyrK Límite: Animals / Humans Idioma: En Revista: Haematologica Año: 2024 Tipo del documento: Article Pais de publicación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Proteínas Serina-Treonina Quinasas / Síndrome de Down / Inhibidores de Proteínas Quinasas / Leucemia-Linfoma Linfoblástico de Células Precursoras / Quinasas DyrK Límite: Animals / Humans Idioma: En Revista: Haematologica Año: 2024 Tipo del documento: Article Pais de publicación: Italia