Type 2 diabetes associated with areca nut usage: A systematic review and meta-analysis.
Prev Med
; 182: 107922, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38428680
ABSTRACT
AIMS/HYPOTHESIS:
This study aimed to evaluate the potential association between chewing areca nuts and the occurrence of type 2 diabetes and to investigate whether chewing status (current chewers or ex-chewers) affects this association.METHODS:
We searched The Cochrane Library, PubMed, and EMBASE databases for relevant studies up to May 21, 2023, using predefined inclusion and exclusion criteria. Three population-based studies conducted in Taiwan were included in the systematic review and meta-analysis.RESULTS:
When combined current or ex-chewers were more likely to develop diabetes (Odds Ratio [OR] = 1.45; 95% confidence interval [CI] 1.30-1.62) compared to the never chewers. Ex-chewers had a higher risk of diabetes (OR 1.53, 95% CI 1.45-1.62) compared to never chewers. However, there was no evidence that current chewers were associated with a higher risk of diabetes compared to never chewers. Male current and ex-chewers were associated with higher risk of diabetes compared with never chewers (OR 1.55, 95% CI 1.49-1.61). For females there was insufficient evidence. CONCLUSIONS/INTERPRETATION:
Existing evidence suggests a link between chewing areca nuts and the development of type 2 diabetes. Therefore, areca chewers should monitor diabetes-related biomarkers.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Prev Med
Año:
2024
Tipo del documento:
Article