[Radiation-induced parotid leiomyosarcoma]. / Léiomyosarcome parotidien en territoire irradié.
Ann Pathol
; 44(3): 210-214, 2024 May.
Article
en Fr
| MEDLINE
| ID: mdl-38448265
ABSTRACT
INTRODUCTION:
First case of radiation-induced parotid leiomyosarcoma. ANATOMO-CLINICAL OBSERVATION A 50-year-old woman with a history of cervical irradiation for Hodgkin's lymphoma presented with a right parotid tumefaction. Examination noted a deep adherent pretragal mass with peripheral facial palsy. A total parotidectomy with intra-operative examination and cervical curage was performed. Histopathological analysis concluded to a grade 3 parotid leiomyosarcoma according to the National Federation of Cancer Centers. Adjuvant radiotherapy was performed. After 24 months of follow-up, the patient presented bone and liver metastases without local recurrence.DISCUSSION:
This is the first case of radiation-induced leiomyosarcoma and the 12th case of parotid leiomyosarcoma described in the literature. The management associates surgery with adjuvant radiotherapy. Follow-up is by clinical examination, parotid MRI, and annual thoracoabdominal CT scan to search for metastases. Recurrences occur during the first year in 40 to 64% of cases, and distant metastases in 40 to 60% of cases. The 5-year survival rate is between 10 and 30%.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Parótida
/
Leiomiosarcoma
/
Neoplasias Inducidas por Radiación
Límite:
Female
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Humans
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Middle aged
Idioma:
Fr
Revista:
Ann Pathol
Año:
2024
Tipo del documento:
Article