Your browser doesn't support javascript.
loading
Granulomatous hepatitis with Crohn's disease: a case report.
Suzuki, Tatsuya; Hayakawa, Yuka; Kaneko, Shun; Takenaka, Kento; Watakabe, Keiya; Kinowaki, Yuko; Takemoto, Akira; Ohtsuka, Kazuo; Asahina, Yasuhiro; Okamoto, Ryuichi.
Afiliación
  • Suzuki T; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
  • Hayakawa Y; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
  • Kaneko S; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. s-kaneko.gast@tmd.ac.jp.
  • Takenaka K; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
  • Watakabe K; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
  • Kinowaki Y; Department of Comprehensive Pathology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
  • Takemoto A; Bioresource Research Center, Tokyo Medical and Dental University, Tokyo, Japan.
  • Ohtsuka K; Endoscopic Unit, Tokyo Medical and Dental University Hospital, Tokyo, Japan.
  • Asahina Y; Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan.
  • Okamoto R; Department of Liver Disease Control, Tokyo Medical and Dental University, Tokyo, Japan.
Clin J Gastroenterol ; 17(3): 551-556, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38502473
ABSTRACT
A 45-year-old man who was regularly followed up for Crohn's disease (CD) and maintained clinical remission with vedolizumab (VDZ). At 37 years old, he was diagnosed CD from longitudinal ulcers in the distal ileum by balloon-assisted enteroscopy (BAE). During the follow-up, liver enzyme elevation, splenomegaly and thrombocytopenia were in progress. Esophagogastric varices suggested chronic liver disease and portal hypertension. Magnetic resonance elastography (MRE) showed liver stiffness of 3.4 kPa and proton density fat fraction (PDFF) of 1.86%. He was diagnosed with granulomatous hepatitis based on a liver biopsy. The hepatic venous pressure gradient (HVPG) was mildly elevated at 7 mmHg, consistent with the pre-sinusoidal portal hypertension due to granulomatous hepatitis. We report a rare case with granulomatous hepatitis diagnosed from liver injury and portal hypertension, despite the stable intestinal symptoms of CD.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Crohn / Granuloma / Hipertensión Portal Límite: Humans / Male / Middle aged Idioma: En Revista: Clin J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Crohn / Granuloma / Hipertensión Portal Límite: Humans / Male / Middle aged Idioma: En Revista: Clin J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: Japón