A story of viral co-infection, co-transmission and co-feeding in ticks: how to compute an invasion reproduction number.
ArXiv
; 2024 Mar 22.
Article
en En
| MEDLINE
| ID: mdl-38562445
ABSTRACT
With a single circulating vector-borne virus, the basic reproduction number incorporates contributions from tick-to-tick (co-feeding), tick-to-host and host-to-tick transmission routes. With two different circulating vector-borne viral strains, resident and invasive, and under the assumption that co-feeding is the only transmission route in a tick population, the invasion reproduction number depends on whether the model system of ordinary differential equations possesses the property of neutrality. We show that a simple model, with two populations of ticks infected with one strain, resident or invasive, and one population of co-infected ticks, does not have Alizon's neutrality property. We present model alternatives that are capable of representing the invasion potential of a novel strain by including populations of ticks dually infected with the same strain. The invasion reproduction number is analysed with the next-generation method and via numerical simulations.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
ArXiv
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos