Recurrent inverse necrotizing infundibular crystalline folliculitis.
J Cutan Pathol
; 51(7): 496-499, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38563487
ABSTRACT
Necrotizing infundibular crystalline folliculitis (NICF) is a rare type of necrotizing folliculitis. The disease typically manifests as folliculocentric papules arising in a seborrheic distribution. Only 23 cases exist in the literature. Most reported cases have arisen spontaneously, but a small number of drug-induced cases in the setting of epidermal-derived growth factor, vascular endothelial-derived growth factor, or PD-1 inhibitor therapy have been reported. Colonization by bacteria and/or yeast occurs frequently. The etiology remains unknown, but some suggest a complex interplay with an aberrant microbiome, sebaceous gland dysfunction, and perturbed EGFR signaling in follicular infundibula. Histopathologic findings include rupture of follicular epithelium, neutrophilic inflammation, and nodular cup-shaped crystal deposits. We present a case of spontaneous, recurrent NICF in an inverse pattern in the inguinal region.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Foliculitis
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Cutan Pathol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos