Emerging Theranostics for Prostate Cancer and a Model of Prostate-specific Membrane Antigen Therapy.
Radiology
; 311(1): e231703, 2024 04.
Article
en En
| MEDLINE
| ID: mdl-38563674
ABSTRACT
There is increasing demand worldwide to develop diagnostic and therapeutic (theranostic) markers for prostate cancer. One target of interest is prostate-specific membrane antigen (PSMA), a protein which is overexpressed in prostate cancer cells. Over the past decade, a growing body of literature has demonstrated that radiolabeled ligands that target PSMA show favorable clinical response and survival outcomes in patients with advanced prostate cancer. This focused review provides background to the development of PSMA as a target, an overview of key studies informing our current approach to radioligand-based imaging and therapy for prostate cancer, and a model for real-world implementation of PSMA theranostics based on an Australian experience.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
/
Biomarcadores de Tumor
/
Glutamato Carboxipeptidasa II
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Medicina de Precisión
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Antígenos de Superficie
Límite:
Humans
/
Male
País/Región como asunto:
Oceania
Idioma:
En
Revista:
Radiology
Año:
2024
Tipo del documento:
Article
Pais de publicación:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA