What does preferential viewing tell us about the neurobiology of recognition memory?
Trends Neurosci
; 47(5): 326-337, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38582659
ABSTRACT
The two tests most widely used in nonhuman primates to assess the neurobiology of recognition memory produce conflicting results. Preferential viewing tests (e.g., visual paired comparison) produce robust impairments following hippocampal lesions, whereas matching tests (e.g., delayed nonmatching-to-sample) often show complete sparing. Here, we review the data, the proposed explanations for this discrepancy, and then critically evaluate those explanations. The most likely explanation is that preferential viewing tests are not a process-pure assessment of recognition memory, but also test elements of novelty-seeking, habituation, and motivation. These confounds likely explain the conflicting results. Thus, we propose that memory researchers should prefer explicit matching tests and readers interested in the neural substrates of recognition memory should give explicit matching tests greater interpretive weight.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Reconocimiento en Psicología
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Neurosci
/
Trends in neurosciences
/
Trends neurosci
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Reino Unido