The Role of Immune Cells in DKD: Mechanisms and Targeted Therapies.
J Inflamm Res
; 17: 2103-2118, 2024.
Article
en En
| MEDLINE
| ID: mdl-38601771
ABSTRACT
Diabetic kidney disease (DKD), is a common microvascular complication and a major cause of death in patients with diabetes. Disorders of immune cells and immune cytokines can accelerate DKD development of in a number of ways. As the kidney is composed of complex and highly differentiated cells, the interactions among different cell types and immune cells play important regulatory roles in disease development. Here, we summarize the latest research into the molecular mechanisms underlying the interactions among various immune and renal cells in DKD. In addition, we discuss the most recent studies related to single cell technology and bioinformatics analysis in the field of DKD. The aims of our review were to explore immune cells as potential therapeutic targets in DKD and provide some guidance for future clinical treatments.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Inflamm Res
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Nueva Zelanda