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Lower Extremity Angiosarcoma: A Life-Threatening Complication of Lymphedema.
Garimella, Vishal; Anand, Nimay; Campbell, Elliott H; Baum, Christian L; Alavi, Afsaneh.
Afiliación
  • Garimella V; At Mayo Clinic, Rochester, Minnesota, USA, Vishal Garimella, MBBS, and Nimay Anand, BA, are Visiting Research Fellows; Elliott H. Campbell, MD, is Dermatology Resident Physician; and Christian L. Baum, MD, and Afsaneh Alavi, MD, are Professors of Dermatology. Acknowledgments: Afsaneh Alavi is on the Board of Directors for the Hidradenitis Suppurativa Foundation and served as a consultant for AbbVie, Almirall, Boehringer Ingelheim, InflaRx, Incyte, Kymera, Novartis, and UCB and investigator for B
Adv Skin Wound Care ; 37(5): 268-270, 2024 May 01.
Article en En | MEDLINE | ID: mdl-38648240
ABSTRACT
ABSTRACT When angiosarcoma, a rare and aggressive tumor of the soft tissue, develops in the setting of chronic lymphedema, it is referred to as Stewart-Treves syndrome. It is usually seen in chronic lymphedema of the upper limbs postmastectomy. Angiosarcoma developing in the lower limb in the setting of chronic lymphedema is rare and has a poor outcome. The presentation of angiosarcoma can vary, ranging from a bleeding papule to a plaque or a subcutaneous mass, which can later progress to ulceration or necrosis. Treatment for Stewart-Treves syndrome is aggressive because of its poor prognosis and usually requires a multidisciplinary approach of surgery, radiation, and chemotherapy. Several theories have been put forth to explain the mechanism of Stewart-Treves syndrome, but it remains ambiguous. The current literature regarding angiosarcoma developing in the setting of chronic lymphedema in the lower limb is limited to single case reports. Herein, the authors report a series of six cases of biopsy-proven angiosarcoma in the setting of lower extremity lymphedema. Providers should include angiosarcoma in the differential diagnosis of ulcerative or vascular tumors arising in the context of lower extremity lymphedema.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extremidad Inferior / Hemangiosarcoma / Linfedema Límite: Humans Idioma: En Revista: Adv Skin Wound Care Asunto de la revista: ENFERMAGEM Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extremidad Inferior / Hemangiosarcoma / Linfedema Límite: Humans Idioma: En Revista: Adv Skin Wound Care Asunto de la revista: ENFERMAGEM Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos