Long-term outcomes of corneal crosslinking.
Curr Opin Ophthalmol
; 35(4): 315-321, 2024 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-38700950
ABSTRACT
PURPOSE OF REVIEW This manuscript summarizes contemporary research from 2018 to 2023 evaluating long-term (≥2âyears) outcomes of corneal crosslinking (CXL) for progressive keratoconus (KCN). RECENT FINDINGS:
The standard Dresden protocol (SDP) has been utilized clinically since the early 2000âs to treat ectatic disorders, primarily progressive KCN and postrefractive ectasia. Various modifications have since been introduced including accelerated and transepithelial protocols, which are aimed at improving outcomes or reducing complications. This review summarizes data demonstrating that the SDP halts disease progression and improves various visual and topographic indices (UDVA, CDVA, Kmax, K1, K2) up to 13âyears postoperatively. Accelerated and transepithelial protocols have been found to be well tolerated alternatives to SDP with similar efficacy profiles. Studies focusing on pediatric populations identified overall higher progression rates after CXL. All protocols reviewed had excellent safety outcomes in adults and children.SUMMARY:
Recent studies revealed that SDP successfully stabilizes KCN long term, and a variety of newer protocols are also effective. Pediatric patients may exhibit higher progression rates after CXL. Further research is required to enhance the efficacy and ease of these protocols.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
/
Riboflavina
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Agudeza Visual
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Colágeno
/
Fármacos Fotosensibilizantes
/
Reactivos de Enlaces Cruzados
/
Queratocono
Límite:
Humans
Idioma:
En
Revista:
Curr Opin Ophthalmol
Asunto de la revista:
OFTALMOLOGIA
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos