S100A9: The Unusual Suspect Connecting Viral Infection and Inflammation.
J Immunol
; 212(10): 1523-1529, 2024 May 15.
Article
en En
| MEDLINE
| ID: mdl-38709994
ABSTRACT
The study of S100A9 in viral infections has seen increased interest since the COVID-19 pandemic. S100A8/A9 levels were found to be correlated with the severity of COVID-19 disease, cytokine storm, and changes in myeloid cell subsets. These data led to the hypothesis that S100A8/A9 proteins might play an active role in COVID-19 pathogenesis. This review explores the structures and functions of S100A8/9 and the current knowledge on the involvement of S100A8/A9 and its constituents in viral infections. The potential roles of S100A9 in SARS-CoV-2 infections are also discussed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Calgranulina A
/
Calgranulina B
/
SARS-CoV-2
/
COVID-19
/
Inflamación
Límite:
Humans
Idioma:
En
Revista:
J Immunol
/
J. immunol
/
Journal of immunology
Año:
2024
Tipo del documento:
Article
País de afiliación:
Canadá
Pais de publicación:
Estados Unidos