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Understanding Creutzfeldt-Jakob disease in Iran: a systematic review of case reports.
Mohebbi, Alireza; Motamedaria, Parastoo; Naderi, Malihe; Hassanpour, Mina; Salavatiha, Zahra; Makouei, Mahsa; Ataei-Pirkooh, Angila.
Afiliación
  • Mohebbi A; Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Motamedaria P; Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Naderi M; Department of Microbiology and Microbial Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
  • Hassanpour M; Department of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran.
  • Salavatiha Z; Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Makouei M; School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Ataei-Pirkooh A; Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
J Int Med Res ; 52(5): 3000605241247706, 2024 May.
Article en En | MEDLINE | ID: mdl-38717041
ABSTRACT

OBJECTIVE:

To systematically review the reported cases of Creutzfeldt-Jakob disease (CJD) in Iran.

METHODS:

A comprehensive literature review of CJD cases in Iran was undertaken using the PubMed®, Scopus® and Google Scholar databases. In addition, the Iranian database MagIran was searched for Persian language reports. Case selection used the following criteria (i) patients of Iranian origin; (ii) publication in peer-reviewed journals or reputable medical databases; (iii) a definitive diagnosis of CJD based on established diagnostic criteria.

RESULTS:

Thirteen cases from twelve reports were included in this systematic review. The majority of the cases were female (11 of 13; 84.6%). The mean ± SD age of patients at hospital admission was 59.38 ± 7.44 years. The findings of the case review suggested that the prevalence of CJD in Iran is not fully established. CJD may be misdiagnosed alongside other clinical signs. The most prevalent early indications of the disease were psychiatric and neurological in nature. A considerable delay in diagnosis was observed in some cases and there was a shortage of brain autopsy records.

CONCLUSION:

Efforts to improve diagnostic capabilities, promote awareness and establish monitoring systems are necessary for managing the challenges of providing an early diagnosis of CJD in Iran.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Creutzfeldt-Jakob Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: J Int Med Res Año: 2024 Tipo del documento: Article País de afiliación: Irán

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Creutzfeldt-Jakob Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: J Int Med Res Año: 2024 Tipo del documento: Article País de afiliación: Irán