Persistence of Treponema pallidum IgM antibodies in serum: What is their meaning?

Ciccarese, Giulia; Capello, Elisabetta; Varesano, Serena; Giacani, Lorenzo; Capurro, Niccolò; Drago, Francesco

Ciccarese, Giulia; Capello, Elisabetta; Varesano, Serena; Giacani, Lorenzo; Capurro, Niccolò; Drago, Francesco.

Afiliación

Ciccarese G; Section of Dermatology, Department of Medical and surgical sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy. Electronic address: giulia.ciccarese@unifg.it.
Capello E; Clinica Neurologica, IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy.
Varesano S; Hygiene Section, IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16132 Genoa, Italy.
Giacani L; Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.
Capurro N; Section of Dermatology, Department of Health Sciences, University of Genoa, IRCCS - Ospedale Policlinico San Martino, Genoa, Italy.
Drago F; Section of Dermatology, Department of Health Sciences, University of Genoa, IRCCS - Ospedale Policlinico San Martino, Genoa, Italy.

Diagn Microbiol Infect Dis ; 109(3): 116341, 2024 Jul.

Article en En | MEDLINE | ID: mdl-38728874

ABSTRACT

ABSTRACT

We studied the detection of Treponema pallidum (TP)-IgM antibodies in the serum of 69 patients treated for syphilis. The persistence of TP-IgM antibodies in serum for more than 3 years was the only clue to suspect an active infection and, therefore, to investigate a central nervous system involvement.

Asunto(s)

Anticuerpos Antibacterianos; Inmunoglobulina M; Sífilis; Treponema pallidum; Humanos; Treponema pallidum/inmunología; Inmunoglobulina M/sangre; Anticuerpos Antibacterianos/sangre; Sífilis/sangre; Sífilis/inmunología; Sífilis/diagnóstico; Sífilis/microbiología; Masculino; Femenino; Adulto; Persona de Mediana Edad; Anciano; Factores de Tiempo

Palabras clave

Neurosyphilis; Syphilis; Treponema pallidum IgM antibodies

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Treponema pallidum / Inmunoglobulina M / Sífilis / Anticuerpos Antibacterianos Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diagn Microbiol Infect Dis Año: 2024 Tipo del documento: Article

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