Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi004-A) from a patient with Congenital Nemaline Myopathy.
Stem Cell Res
; 77: 103435, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38733812
ABSTRACT
We used a non-integrated reprogramming approach to establish a human induced pluripotent stem cell (hiPSC) line (INNDSUi004-A) from the skin fibroblasts of a 13-year-old female individual with Congenital Nemaline Myopath. The cells obtained have typical characteristics of embryonic stem cells, show expression of specific pluripotency markers, and can differentiate into three germ layers in vitro. This iPSC cell line has the genetic information of the patient and is a good model for studying disease mechanisms and developing novel therapies.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diferenciación Celular
/
Miopatías Nemalínicas
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Células Madre Pluripotentes Inducidas
Límite:
Adolescent
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Female
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Humans
Idioma:
En
Revista:
Stem Cell Res
Año:
2024
Tipo del documento:
Article