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Preparation of hollow double-layer Pt@CeO2 nanospheres as oxidase mimetics for the colorimetric-fluorescent-SERS triple-mode detection of glutathione in serum.
Liao, Yiquan; He, Yichang; Zhang, Bin; Ma, Ye; Zhao, Minggang; Xu, Ruiqi; Cui, Hongzhi.
Afiliación
  • Liao Y; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China.
  • He Y; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China.
  • Zhang B; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China.
  • Ma Y; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China.
  • Zhao M; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China. Electronic address: zhaomg@ouc.edu.cn.
  • Xu R; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China.
  • Cui H; School of Materials Science and Engineering, Ocean University of China, 266100, Qingdao, PR China.
Talanta ; 276: 126234, 2024 Aug 15.
Article en En | MEDLINE | ID: mdl-38749161
ABSTRACT
Glutathione (GSH) is an essential antioxidant in the human body, but its detection is difficult due to the interference of complex components in serum. Herein, hollow double-layer Pt@CeO2 nanospheres were developed as oxidase mimetics, and the light-assisted oxidase mimetics effects were found. The oxidase activity was enhanced significantly by utilizing the synergistic effect of Schottky junction and the localized surface plasmon resonance (LSPR) of Pt under UV light. A novel GSH colorimetric-fluorescent-SERS sensing platform was established, with the sensing performance notably boosted by using the light-assisted oxidase mimetics effects. This platform boasts an exceptionally low detection limit (LOD) of 0.084 µM, while the detection time was shortened from 10 min to just 2 min. The anti-interference detection with high recovery rate (96.84%-107.4 %) in real serum made it be promising for practical application.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxidorreductasas / Platino (Metal) / Cerio / Colorimetría / Resonancia por Plasmón de Superficie / Nanosferas / Glutatión Límite: Humans Idioma: En Revista: Talanta Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxidorreductasas / Platino (Metal) / Cerio / Colorimetría / Resonancia por Plasmón de Superficie / Nanosferas / Glutatión Límite: Humans Idioma: En Revista: Talanta Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos