Transzonular moxifloxacin and dexamethasone delivery in phacoemulsification: A novel dropless regimen.
Indian J Ophthalmol
; 72(8): 1147-1149, 2024 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-38767558
ABSTRACT
PURPOSE:
To assess the safety and efficacy of transzonular moxifloxacin and dexamethasone versus standard postoperative topical drug regimen in phacoemulsification.DESIGN:
Nonrandomized prospective study.METHODS:
The study included 100 eyes of 100 age and gender-matched individuals with senile cataract undergoing routine phacoemulsification. The patients were consecutively divided into transzonular (TZ = 50) and topical (TP = 50) groups. Both the groups were followed up for 4 weeks and assessed for intraocular inflammation, visual acuity, changes in intraocular pressure (IOP), and any adverse events.RESULTS:
The grades of inflammation were significantly lower in TZ as compared to the TP group ( P < 0.001). The IOP remained normal and comparable in both the groups. Most of the patients in the two groups attained a visual acuity of 0.2 or better at the end of the follow-up. No adverse effects and increased rate of endophthalmitis were noted in TZ group.CONCLUSION:
A one-time peroperative TZ moxifloxacin and dexamethasone combination is a safe and effective method to control postoperative inflammation after cataract surgery. A word of caution though, due precautions to be exercised to prevent the risk of inflammation and endophthalmitis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dexametasona
/
Agudeza Visual
/
Facoemulsificación
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Fluoroquinolonas
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Moxifloxacino
/
Glucocorticoides
Límite:
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Indian J Ophthalmol
Año:
2024
Tipo del documento:
Article
País de afiliación:
India