Glucose-6-phosphate dehydrogenase enzyme deficiency as a diagnostic factor of diabetes mellitus: An original study.
J Oral Maxillofac Pathol
; 28(1): 96-99, 2024.
Article
en En
| MEDLINE
| ID: mdl-38800416
ABSTRACT
Background:
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common genetic disorders affecting approximately 400 million people worldwide. Several recent studies have reported a relationship between G6PD deficiency and the incidence of diabetes.Objectives:
The aim of the present study was to evaluate and compare levels of G6PD deficiency in diabetes mellitus patients. Materials andMethods:
G6PD activity and fasting glucose levels were measured in blood samples of 49 diabetic patients and 21 healthy controls.Results:
G6PD activity was decreased in patients with diabetes mellitus as compared to healthy controls and showed that overall G6PD deficiency was significantly associated with diabetes mellitus as compared to nondiabetics.Conclusion:
The study concluded that G6PD deficiency is noted in diabetics than in nondiabetics and can be a biomarker of oxidative stress and poor glycemic control in diabetes mellitus.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Oral Maxillofac Pathol
Año:
2024
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
India