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[A new sesquiterpene from Syringa oblata].
Tai, Bada-Lahu; Sun, Tian-Xia; Dai, Nayin-Tai; Yu, Mu-Yao; Liu, Qi; Huang, Lu-Qi; Zheng, Han.
Afiliación
  • Tai BL; NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine (Mongolian Medicine), Mongolian Medical College, Inner Mongolia Minzu University Tongliao 028000, China State Key Laboratory for Quality Insurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia
  • Sun TX; Jilin Ginseng Academy, Changchun University of Chinese Medicine Changchun 130117, China.
  • Dai NT; NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine (Mongolian Medicine), Mongolian Medical College, Inner Mongolia Minzu University Tongliao 028000, China.
  • Yu MY; State Key Laboratory for Quality Insurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
  • Liu Q; State Key Laboratory for Quality Insurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
  • Huang LQ; State Key Laboratory for Quality Insurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
  • Zheng H; State Key Laboratory for Quality Insurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi ; 49(9): 2461-2467, 2024 May.
Article en Zh | MEDLINE | ID: mdl-38812145
ABSTRACT
In this study, the chemical components of ethanol extract from the aromatic parts of Syringa oblata were systematically separated and purified by silica gel column chromatography, thin layer plate preparation and liquid phase preparation. Combined with ultraviolet analyzer(UV), infrared analyzer(IR), nuclear magnetic resonance analyzer(NMR), high resolution mass spectrometer(HR-ESI-MS), X-ray diffraction and other spectrum technology as well as literature physicochemical data comparison methods for structural identification, a total of 10 compounds were identified. They were identified as oblatanoid D(1),(-)-T-muurolol(2), oblatanoid E-G(3-5), 14-noreudesma-3-hydroxy-3-en-2,9-dione(6), 1-isopropyl-2,7-dimethylnaphthalene(7), isocoradiol(8), α-calacorene(9), cadin-4-en-1-ß-ol(10). Compound 1 is a new sesquiterpene compound that has not been reported, and the other 9 compounds are isolated from S. oblata for the first time. The compound 1 has a significant protective effect on the LPS-induced inflammatory injury model of RAW264.7 cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sesquiterpenos / Syringa Límite: Animals Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Asunto de la revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Año: 2024 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sesquiterpenos / Syringa Límite: Animals Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Asunto de la revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Año: 2024 Tipo del documento: Article