Shared genetic basis connects smoking behaviors and bone health: insights from a genome-wide cross-trait analysis.
J Bone Miner Res
; 39(7): 918-928, 2024 Aug 05.
Article
en En
| MEDLINE
| ID: mdl-38843381
We conducted a comprehensive genome-wide cross-trait analysis to investigate the shared genetic basis and causal relationship underlying smoking and osteoporosis. Our findings revealed that smoking and eBMD are inherently linked through biological pleiotropy. Importantly, our study discovered that quitting smoking significantly reduced the risk of lower eBMD. We recommend individuals to avoid, reduce, or quit smoking as early as possible to protect bone health.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fumar
/
Densidad Ósea
/
Estudio de Asociación del Genoma Completo
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Bone Miner Res
Asunto de la revista:
METABOLISMO
/
ORTOPEDIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Reino Unido