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Time-varying brentuximab vedotin pharmacokinetics and weight-based dosing in paediatric patients despite lower exposure in those aged 2 to <6 and 6-11 years.
Zhang, Daping; Zhang, Zufei; Lee, Anthony; Fenton, Keenan; Jain, Shweta; Garg, Amit; Chia, Yen Lin.
Afiliación
  • Zhang D; Translational Clinical Sciences, Research and Development, Pfizer, Bothell, Washington, USA.
  • Zhang Z; Clinical Pharmacology and Translational Sciences, Oncology Research and Development, Pfizer, Bothell, Washington, USA.
  • Lee A; Clinical Pharmacology and Translational Sciences, Oncology Research and Development, Pfizer, Bothell, Washington, USA.
  • Fenton K; Oncology Statistics, Oncology Research and Development, Pfizer, Bothell, Washington, USA.
  • Jain S; Oncology Research and Development, Pfizer, Bothell, Washington, USA.
  • Garg A; Clinical Pharmacology and Translational Sciences, Oncology Research and Development, Pfizer, South San Francisco, California, USA.
  • Chia YL; Translational Clinical Sciences, Research and Development, Pfizer, South San Francisco, California, USA.
Br J Clin Pharmacol ; 90(9): 2299-2313, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38866401
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peso Corporal / Inmunoconjugados / Brentuximab Vedotina Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peso Corporal / Inmunoconjugados / Brentuximab Vedotina Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido