Comprehensive transcriptomic analysis unveils macrophage-associated genes for establishing an abdominal aortic aneurysm diagnostic model and molecular therapeutic framework.

Wu, Zhen; Yu, Weiming; Luo, Jie; Shen, Guanghui; Cui, Zhongqi; Ni, Wenxuan; Wang, Haiyang

Wu, Zhen; Yu, Weiming; Luo, Jie; Shen, Guanghui; Cui, Zhongqi; Ni, Wenxuan; Wang, Haiyang.

Afiliación

Wu Z; Department of Vascular and Interventional Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.
Yu W; Department of Vascular and Interventional Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.
Luo J; General Surgery, Thyroid Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510000, Guangdong, China.
Shen G; Department of Vascular and Interventional Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.
Cui Z; Department of Clinical Laboratory, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Ni W; Department of Vascular and Interventional Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.
Wang H; Department of Clinical Laboratory, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.

Eur J Med Res ; 29(1): 323, 2024 Jun 12.

Article en En | MEDLINE | ID: mdl-38867262

Asunto(s)

Aneurisma de la Aorta Abdominal; Perfilación de la Expresión Génica; Macrófagos; Aneurisma de la Aorta Abdominal/genética; Aneurisma de la Aorta Abdominal/diagnóstico; Humanos; Animales; Macrófagos/metabolismo; Ratones; Perfilación de la Expresión Génica/métodos; Redes Reguladoras de Genes; Modelos Animales de Enfermedad; Transcriptoma; Biomarcadores/metabolismo

Palabras clave

Abdominal aortic aneurysm; Atherosclerosis; Machine learning; Macrophage marker genes; Single-cell sequencing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Abdominal / Perfilación de la Expresión Génica / Macrófagos Límite: Animals / Humans Idioma: En Revista: Eur J Med Res Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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