Bacteria in metastatic sites: Unveiling hidden players in cancer progression.
Cancer Cell
; 42(7): 1142-1146, 2024 Jul 08.
Article
en En
| MEDLINE
| ID: mdl-38876104
ABSTRACT
Bacteria exhibit key features of cancer metastasis, such as motility, invasion, and modulation of the tumor microenvironment. They migrate through lymphatic and blood systems, invade metastatic tissues, and alter local microenvironments to support metastatic growth. Bacteria also shape the tumor microenvironment, affecting immune responses and inflammation, which influence tumor progression and therapy response. While they hold therapeutic potential, challenges like contamination and complex characterization persist, necessitating advanced sequencing and research for clinical application.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Progresión de la Enfermedad
/
Microambiente Tumoral
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Metástasis de la Neoplasia
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Neoplasias
Límite:
Animals
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Humans
Idioma:
En
Revista:
Cancer Cell
Asunto de la revista:
NEOPLASIAS
Año:
2024
Tipo del documento:
Article