RNA: De-silencing to the rescue.

Held, James P; Patel, Maulik R

Held, James P; Patel, Maulik R.

Afiliación

Held JP; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Patel MR; Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Department of Evolutionary Studies, Vanderbilt University, VU Box #34-1634, Nashville, TN 37232, USA; Diabetes Research and Training Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Quantitative Systems Biology Center, Vanderbilt University, Nashville, TN 37232, USA. Electro

Curr Biol ; 34(12): R573-R575, 2024 Jun 17.

Article en En | MEDLINE | ID: mdl-38889679

ABSTRACT

ABSTRACT

The fate of transcribed RNA dictates cellular function. A new study finds that mutations in specific RNA processing machinery genes result in de-silencing of a transcript encoding a subunit of the mitochondrial electron transport chain and rescue of a mitochondrial respiratory complex I defect.

Asunto(s)

Complejo I de Transporte de Electrón; Complejo I de Transporte de Electrón/genética; Complejo I de Transporte de Electrón/metabolismo; Mitocondrias/genética; Mitocondrias/metabolismo; Animales; Mutación; Silenciador del Gen

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complejo I de Transporte de Electrón Límite: Animals Idioma: En Revista: Curr Biol Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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