40 years of researching the Del phenotype results in a change of transfusion practice.
Transfusion
; 64(7): 1187-1190, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38899801
ABSTRACT
Anti-D cannot agglutinate red cells of any Del phenotype in routine serology. Many individuals with East Asian ancestry who type D-negative in serology harbor a Del phenotype. Almost all such individuals carry one distinct DEL variant, dubbed Asian-type DEL, known as RHD*01EL.01, RHD*DEL1, RHDc.1227G>A, formerly known as RHD(K409K). Clinical evidence strongly suggests that Asian-type DEL individuals can safely be transfused with RhD-positive blood and do not need anti-D prophylaxis in pregnancy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fenotipo
/
Sistema del Grupo Sanguíneo Rh-Hr
/
Transfusión Sanguínea
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Transfusion
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos