Is serum BDNF level reliable parameter in detecting of dental anxiety before impacted third molar surgery?
Med Oral Patol Oral Cir Bucal
; 29(4): e584-e590, 2024 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-38907644
ABSTRACT
BACKGROUND:
Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to determine the relationship between dental anxiety and BDNF serum level through impacted third molar surgery. MATERIAL ANDMETHODS:
In this randomized, double-blind, cross-sectional study, the sample included patients who had been admitted for the impacted third molar extraction under local anesthesia between January to November 2020. The primary predictor variable was serum BDNF level and the second predictor variable was dental anxiety scores before and after operation in patients. The primary outcome variable was the correlation between anxiety scores (APAIS, MDAS, STAI, VAS) and serum BDNF level. The sample included 55 patients (22 Male, 33 Female) aged 18 to 42 (24,2+5,55).RESULTS:
Comparison of pre-operative scores (APAIS, MDAS, STAI, VAS and BDNF) and post-operative scores were statistically significant (P < .05). Post-operatively, MDAS and VAS scores decreased, while BDNF levels and STAI scores increased compared to the preoperative scores. BDNF was not correlated with APAIS, MDAS, STAI, and VAS preoperatively and postoperatively.CONCLUSIONS:
There may be a relationship between serum BDNF level and dental anxiety scale, but, no correlation was found between them.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Extracción Dental
/
Diente Impactado
/
Ansiedad al Tratamiento Odontológico
/
Factor Neurotrófico Derivado del Encéfalo
/
Tercer Molar
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Med Oral Patol Oral Cir Bucal
Asunto de la revista:
ODONTOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Turquía