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Introducing a Novel Innovative Technique for the Recording and Interpretation of Dynamic Coronary Angiography.
Nguyen, Thach; Ngo, Khiem; Vu, Tri Loc; Nguyen, Hien Q; Pham, Dat H; Kodenchery, Mihas; Zuin, Marco; Rigatelli, Gianluca; Nanjundappa, Aravinda; Gibson, Michael.
Afiliación
  • Nguyen T; Cardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.
  • Ngo K; School of Medicine, Tan Tao University, Duc Hoa 82000, Long An, Vietnam.
  • Vu TL; Department of Medicine, University of Texas Rio Grande Valley, Valley Baptist Medical Center, Harlingen, TX 78550, USA.
  • Nguyen HQ; Cardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.
  • Pham DH; Cardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.
  • Kodenchery M; Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USA.
  • Zuin M; Cardiovascular Research Laboratories, Methodist Hospital, Merrillville, IN 46410, USA.
  • Rigatelli G; Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
  • Nanjundappa A; Interventional Cardiology Unit, Division of Cardiology, AULSS6 Ospedali Riuniti Padova Sud, 35043 Padova, Italy.
  • Gibson M; Peripheral Interventions, Cardiovascular Department, Cleveland Clinics Main Campus, Cleveland, OH 44195, USA.
Diagnostics (Basel) ; 14(12)2024 Jun 17.
Article en En | MEDLINE | ID: mdl-38928697
ABSTRACT
In the study of coronary artery disease (CAD), the mechanism of plaque formation and development is still an important subject for investigation. A limitation of current coronary angiography (CAG) is that it can only show static images of the narrowing of arterial channels without identifying the mechanism of the disease or predicting its progression or regression. To address this limitation, the CAG technique has been modified. The new approach emphasizes identifying and analyzing blood flow patterns, employing methodologies akin to those used by hydraulic engineers for fluid or gas movement through domestic or industrial pipes and pumps. With the new technique, various flow patterns and arterial phenomena-such as laminar, turbulent, antegrade, retrograde, and recirculating flow and potentially water hammer shock and vortex formation-are identified, recorded, and classified. These phenomena are then correlated with the presence of lesions at different locations within the coronary vasculature. The formation and growth of these lesions are explained from the perspective of fluid mechanics. As the pathophysiology of CAD and other cardiovascular conditions becomes clearer, new medical, surgical, and interventional treatments could be developed to reverse abnormal coronary flow dynamics and restore laminar flow, leading to improved clinical outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
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