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Interweaving the Numerical harmonic symmetry principles of the K+ Pore ion channel momentum.
Ben-Abu, Yuval.
Afiliación
  • Ben-Abu Y; Physics Unit, Sapir Academic College, Sderot, Hof Ashkelon, 79165, Israel; Clarendon Laboratory, Department of Physics, University of Oxford, OX1 3PU, UK. Electronic address: yuvalb@sapir.ac.il.
Neurochem Int ; 178: 105797, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38942118
ABSTRACT
K+ channels exist in all living systems. They allow a selective transition to the K+ ion, which enables the activity of various vital tissues such as muscle cells, neurons, and even bacteria and plants. Despite the mechanism variation in the gating process of K+ channels in different tissues, the selectivity for the K+ ion is preserved and the electrochemical cascade is maintained in these tissues. The electrochemical gradient of the K+ ion is very close to the diffusion rate of K+ ions in bulk water. On the molecular level, how does a K+ ion move across the ion conduction pathway? There are many molecular models that describe and answer this question, however, this is rarely described on the macro level. Here, a physical model can serve as a very good basis for enabling a deeper understanding of the K+ ion for ion transport. Classical physical energy and linear and angular momentum laws can provide a good explanation as to how and what happens to K+ ions when they pass through an ion conduction pathway. This model describes the passage of the ion even before it enters the ion conduction path until the last ion at the end exits. The simulation described here is fascinating and depicts the state of the ion at the farthest end released at almost the same speed as the first ion initially, while all the other ions remain almost at rest. How does this occur? What happens if we change the size or mass of the ion? In this work, I describe this principle and the related problems that could be studied.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potasio / Canales de Potasio Límite: Animals / Humans Idioma: En Revista: Neurochem Int Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potasio / Canales de Potasio Límite: Animals / Humans Idioma: En Revista: Neurochem Int Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido