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Pharmacological actions of the bioactive compounds of Epimedium on the male reproductive system: current status and future perspective.
Liu, Song-Po; Li, Yun-Fei; Zhang, Dan; Li, Chun-Yang; Dai, Xiao-Fang; Lan, Dong-Feng; Cai, Ji; Zhou, He; Song, Tao; Zhao, Yan-Yu; He, Zhi-Xu; Tan, Jun; Zhang, Ji-Dong.
Afiliación
  • Liu SP; Department of Immunology, Zunyi Medical University, Zunyi 563000, China.
  • Li YF; Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi 563000, China.
  • Zhang D; Department of Medical Genetics, Zunyi Medical University, Zunyi 563000, China.
  • Li CY; Department of Immunology, Zunyi Medical University, Zunyi 563000, China.
  • Dai XF; Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi 563000, China.
  • Lan DF; Department of Respiratory Medicine, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi 563000, China.
  • Cai J; Zunyi Medical University Library, Zunyi 563000, China.
  • Zhou H; Department of Immunology, Zunyi Medical University, Zunyi 563000, China.
  • Song T; Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi 563000, China.
  • Zhao YY; Department of Immunology, Zunyi Medical University, Zunyi 563000, China.
  • He ZX; Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi 563000, China.
  • Tan J; Department of Immunology, Zunyi Medical University, Zunyi 563000, China.
  • Zhang JD; Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi 563000, China.
Asian J Androl ; 2024 Jul 09.
Article en En | MEDLINE | ID: mdl-38978290
ABSTRACT
ABSTRACT Compounds isolated from Epimedium include the total flavonoids of Epimedium, icariin, and its metabolites (icaritin, icariside I, and icariside II), which have similar molecular structures. Modern pharmacological research and clinical practice have proved that Epimedium and its active components have a wide range of pharmacological effects, especially in improving sexual function, hormone regulation, anti-osteoporosis, immune function regulation, anti-oxidation, and anti-tumor activity. To date, we still need a comprehensive source of knowledge about the pharmacological effects of Epimedium and its bioactive compounds on the male reproductive system. However, their actions in other tissues have been reviewed in recent years. This review critically focuses on the Epimedium, its bioactive compounds, and the biochemical and molecular mechanisms that modulate vital pathways associated with the male reproductive system. Such intrinsic knowledge will significantly further studies on the Epimedium and its bioactive compounds that protect the male reproductive system and provide some guidances for clinical treatment of related male reproductive disorders.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Asian J Androl Asunto de la revista: MEDICINA REPRODUTIVA / UROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Asian J Androl Asunto de la revista: MEDICINA REPRODUTIVA / UROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: China