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Surgical Nonresponders in Zenker Diverticulum and Lower Esophageal Pathology (POUCH Collaborative).
Brown, Johnathan; McCoy, Nicole; Allen, Jacqui; Altaye, Mekibib; Amin, Milan; Bayan, Semirra; Belafsky, Peter; DeSilva, Brad; Dion, Greg; Ekbom, Dale; Friedman, Aaron; Fritz, Mark; Giliberto, John Paul; Guardiani, Elizabeth; Johnson, Christopher; Kasperbauer, Jan; Kim, Brandon; Krekeler, Brittany N; Kuhn, Maggie; Kwak, Paul; Ma, Yue; Madden, Lyndsay L; Matrka, Laura; Mayerhoff, Ross; Piraka, Cyrus; Rosen, Clark A; Tabangin, Meredith; Wahab, Shaun; Wilson, Keith; Wright, Carter; Young, VyVy N; Postma, Gregory; Howell, Rebecca J.
Afiliación
  • Brown J; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • McCoy N; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Allen J; Department of Surgery, University of Auckland, Auckland, New Zealand.
  • Altaye M; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Amin M; Department of Otolaryngology-Head and Neck Surgery, New York University, New York, New York, USA.
  • Bayan S; Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • Belafsky P; Department of Otolaryngology-Head and Neck Surgery, University of California - Davis, Davis, California, USA.
  • DeSilva B; Department of Otolaryngology-Head and Neck Surgery, Ohio State University, Columbus, Ohio, USA.
  • Dion G; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Ekbom D; Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • Friedman A; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Fritz M; Department of Otolaryngology-Head and Neck Surgery, University of Kentucky, Lexington, Kentucky, USA.
  • Giliberto JP; Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.
  • Guardiani E; Department of Otolaryngology-Head and Neck Surgery, University of Maryland, Baltimore, Maryland, USA.
  • Johnson C; Department of Otolaryngology-Head and Neck Surgery, Medical College of Georgia at Augusta University Health, Augusta, Georgia, USA.
  • Kasperbauer J; Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
  • Kim B; Department of Otolaryngology-Head and Neck Surgery, Ohio State University, Columbus, Ohio, USA.
  • Krekeler BN; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Kuhn M; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Kwak P; Department of Communication Sciences and Disorders, College of Allied Health Sciences, University of Cincinnati, Cincinnati, Ohio, USA.
  • Ma Y; Department of Otolaryngology-Head and Neck Surgery, University of California - Davis, Davis, California, USA.
  • Madden LL; Department of Otolaryngology-Head and Neck Surgery, New York University, New York, New York, USA.
  • Matrka L; Department of Otolaryngology-Head and Neck Surgery, University of California - San Francisco, San Francisco, California, USA.
  • Mayerhoff R; Department of Otolaryngology-Head and Neck Surgery, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Piraka C; Department of Otolaryngology-Head and Neck Surgery, Ohio State University, Columbus, Ohio, USA.
  • Rosen CA; Department of Otolaryngology-Head and Neck Surgery, Henry Ford Health System, Detroit, Michigan, USA.
  • Tabangin M; Department of Gastroenterology/Hepatology, Henry Ford Health System, Detroit, Michigan, USA.
  • Wahab S; Department of Otolaryngology-Head and Neck Surgery, University of California - San Francisco, San Francisco, California, USA.
  • Wilson K; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Wright C; Department of Radiology, University of Cincinnati, Cincinnati, Ohio, USA.
  • Young VN; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Postma G; Department of Otolaryngology-Head and Neck Surgery, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Howell RJ; Department of Otolaryngology-Head and Neck Surgery, University of California - San Francisco, San Francisco, California, USA.
Laryngoscope ; 2024 Jul 09.
Article en En | MEDLINE | ID: mdl-38979706
ABSTRACT

OBJECTIVE:

To identify characteristics of patients who have poor improvement in symptoms following surgical management of Zenker Diverticulum (ZD).

METHODS:

Prospective, multicenter cohort study of all individuals enrolled in the Prospective OUtcomes of Cricopharyngeus Hypertonicity (POUCH) Collaborative who underwent surgical repair of ZD between August 2017 and January 2024. Patient demographics, esophagrams, and the 10-item Eating Assessment Tool (EAT-10) pre- and post-procedure were obtained from a REDCap database. t-tests, Wilcoxon rank sum tests, Chi-square or Fisher's exact tests were used to compare the characteristics. Patients with <50% improvement in their EAT-10 scores were deemed surgical nonresponders (SNRs). Those with ≥50% improvement in their EAT-10 scores were deemed surgical responders (SRs).

RESULTS:

A total of 184 patients were prospectively followed after undergoing either open or endoscopic surgical management. Twenty-two patients (12%) were deemed SNRs. Preoperative presence of a hiatal hernia was statistically significant characteristic between the SNRs (63.6%) and SRs (32.1%) (p = 0.004). Size of the ZD and history of previous ZD surgery was not a significant characteristic. The length of stay and complication rate were not statistically different between the groups.

CONCLUSION:

Coexistent esophageal pathology may lead to poor symptomatic improvement following ZD surgery. Preoperative workup of other esophageal disorders is recommended to detect likely SNRs. For SNRs, further esophageal workup may be necessary to evaluate for other esophageal causes related to poor symptomatic improvement following ZD surgery. LEVEL OF EVIDENCE Level 3 Laryngoscope, 2024.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos